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Multi-Drug Resistance and Drug Metabolism > Drug and Xenobiotic Metabolism > Substrates, Inducers, Inhibitors

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Sigma

Terfenadine alcohol metabolite


Synonym:	α-[4-(3-Hydroxy-2-methylprop-2-yl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Linear Formula:	C₃₂H₄₁NO₃
Molecular Weight:	487.67

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Description

Biochem/physiol Actions

CYP3A4 metabolitye of terfenadine

Properties

color	white
mp	123-128 °C
storage temp.	2-8°C

Safety

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany	3

References

reference

Chen, T.M., et al. J. Pharm. Biomed. Anal. 9, 929-933, (1991)

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